tumour

The Interplay Between Tumour Surgery and Cancer Metastasis

The primary treatment option for the majority of malign tumors is surgery. However, growing experimental and clinical evidence demonstrates that surgery itself can accelerate metastasis development. Reasons for that are numerous: Growing experimental and clinical evidence demonstrates that surgery itself can accelerate metastasis development.  Tumor shedding Damage to the patients’ tissues during surgery has been …

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The Importance of Cancer-cell Communication, and Could we Target it in a Smarter Way

Crosstalk among cancer cells and between cancer cells and the tumour microenvironment plays a crucial role in tumour development and progression (1). This communication is a two-way process (inside-out and outside-in) and can be realized through both direct contact and indirectly. (2,3,4,5,6) The importance of signaling pathways Cells continuously release billions of signalling molecules. In …

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