The Importance of Cancer-cell Communication, and Could we Target it in a Smarter Way

Crosstalk among cancer cells and between cancer cells and the tumour microenvironment plays a crucial role in tumour development and progression (1). This communication is a two-way process (inside-out and outside-in) and can be realized through both direct contact and indirectly. (2,3,4,5,6) The importance of signaling pathways Cells continuously release billions of signalling molecules. In …

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